BRITAIN PERMITS WORLD'S FIRST 'THREE-PARENT' IVF BABIES

  Britain become the first country to allow a "three-parent" IVF technique which doctors say will prevent some inherited incurable diseases but which critics see as a step towards creating designer babies.

The treatment is known as "three-parent" in vitro fertilisation (IVF) because the babies, born from genetically modified embryos, would have DNA from a mother, a father and from a female donor. It is designed to help families with mitochondrial diseases, incurable conditions passed down the maternal line that affect around one in 6,500 children worldwide.

After an emotionally charged 90-minute debate that some lawmakers criticised as being too short for such a serious matter, parliament voted 382 to 128 in favour of the technique, called mitochondrial donation.

The vote paves the way for a medical world first for Britain -- which along with the United States has been at the forefront of scientific research on the treatments -- but one that is fiercely disputed by some religious groups and other critics.

The process involves intervening in the fertilisation process to remove possibly faulty mitochondria, which can cause inherited conditions such as fatal heart problems, liver failure, brain disorders, blindness and muscular dystrophy. Mitochondrial DNA is separate from DNA found in the cell nucleus and does not affect human characteristics such as hair or eye colour, appearance or personality traits.

"I wouldn't stand here and defend the concept of designer babies -- choosing the colour of the eyes and all the rest of it. This is purely about dealing with those terrible, terrible illnesses," opposition Labour lawmaker Andrew Miller, chair of parliament's science and technology committee, told the debate.

International charities, advocacy groups and scientists had urged Britain to pass laws to allow the treatment, saying it brought a "first glimmer of hope" for some families of having a baby who could live without suffering.

"We have finally reached a milestone in giving women an invaluable choice, the choice to become a mother without fear of passing on a lifetime under the shadow of mitochondrial disease to their child," Robert Meadowcroft, chief executive of the Muscular Dystrophy Campaign, said following the vote.

in an open letter to lawmakers, 11 international campaign groups, including the U.S. United Mitochondrial Disease Foundation, described the condition as "unimaginably cruel".

"It strips our children of the skills they have learned, inflicts pain that cannot be managed and tires their organs one by one until their little bodies cannot go on any more," they wrote.

Lawmakers were given a free vote on the issue, and Prime  inister David Cameron's spokesman said the British leader had voted to support it, adding it was not "about playing God".

He has a particular sympathy with those parents whose children are born with very serious illnesses, that in nearly all cases end their lives prematurely," the spokesman said, referring to Cameron's son Ivan who suffered from cerebral palsy and severe epilepsy and died aged six in 2009.

Proposed new laws allowing the treatments to be carried out in Britain still have to be approved by the upper house, which commentators expect to endorse parliament's support.

In another development, a report by a high-level group of American academics has concluded that the three-parent IVF technique should not be used to create baby girls until more is known about the safety implications, The so-called “three-parent” embryo technology should initially be confined to male embryos only because of the risk of creating “genetically modified” girls that will pass on defective DNA to subsequent generations, according to the US National Academies of Sciences, Engineering and Medicine (NAS).